Co-Testing for Cervical Cancer is Best, But Not Perfect

05 Июля, 2018, 22:04 | Auteur: Yves Courtet
  • HPV test is better than Pap smear at detecting precancerous cervical changes study says

Pap smear tests and HPV tests are designed in such a way that they help in early detection of precancerous and cancerous processes of cervical cancers so as to avoid contracting those cancers. "When we think about cervical cancer screening, we want to think about it in the framework of how do we get this test in the hands of all women?"

The HPV infection is the most common sexually transmitted infection and is usually eliminated by the immune system within a year or two. But when an infection persists, it can cause cellular changes that develop into precancerous lesions and, eventually, malignancies.

The virus is now known to be the main cause of cervical cancer. The study is important in informing screening methods as the American Cancer Society estimates around 13,000 American women will be diagnosed with cervical cancer, and about 4,170 will die from it.

Women who have a positive Pap test, generally get a colposcopy, which is an even closer examination of the cervix, vagina and vulva for signs of disease. He wrote in an email that this new study actually shows the small but significant benefit of co-testing. At the start, half of the women were tested for HPV while the other half had a Pap smear screening.

"This is one study", he said.

For the study, the researchers randomly assigned more than 19,000 women aged 25 and older to either Pap testing alone or HPV testing alone. It was published this month in the Journal of the American Medical Association. These conditions can be treated before they progress to cervical cancer. Gynecologic oncologist Dr. Kathleen Schmeler at the University of Texas MD Anderson Cancer Center, said in a statement, "In our world, this study is going to be a pretty big deal, in a good way".

"That's a lot of women that are unnecessarily anxious", she says.

Читайте также: Mother’s lifestyle choices linked to obesity risk in adolescents: Know detail

In 2014 FDA approved the first HPV test. As a result, the study's results are likely an underestimate, as underserved women were not included, although they may face the highest risk of developing cervical cancer, the authors said.

HPV test will provide accurate results of cervical cancer than Pap smear.

"Although cervical screening guidelines from a number of organizations have recommended primary HPV testing based on the natural history of cervical cancer, cross-sectional studies, studies where HPV-based screening was part of a screening group, or where studies ultimately evolved into primary HPV evaluations, none of these studies were designed specifically to examine HPV testing as the primary screening modality", Ogilvie reported. By 48 months, there were significantly fewer cases of CIN2+ and CIN3+ detected among all age groups in the intervention group.

Women in the HPV group who screened negative returned at 48 months, while women in the cytology group who were negative at 24 months returned at 48 months, and both groups received co-testing at the 48 month exit. This type of cancer is mostly caused by the human papillomavirus (HPV), in as much as 99% of all cases.

"What our study shows is that by using HPV testing, we detect precancerous lesions earlier", says lead author Dr. Gina Ogilvie.

"We really can't answer the question around whether co-testing is better than either alone". She says the method of testing comes second to being sure that all women, especially high prevalence groups like black and hispanic women, are able to get the testing they need. The researchers observed that women who were HPV-negative at baseline were significantly less likely to have CIN2+ or CIN3+ at 48 months compared with those who had negative Pap smear results at baseline. The Canadian task force does note that HPV testing may be recommended once more research is available. The Pap smear worked, he said, only because women were tested often and because cervical cancer grows slowly. Those in the Pap group who tested negative returned two years later for another and, if they tested negative again, returned at the end of the four-year study.

При любом использовании материалов сайта и дочерних проектов, гиперссылка на обязательна.
«» 2007 - 2019 Copyright.
Автоматизированное извлечение информации сайта запрещено.

Код для вставки в блог

Conseillé:

  • Mother accused of selling her son, trying to sell 2 young daughters

    Mother accused of selling her son, trying to sell 2 young daughters

    Garza, 29, was arrested and charged with the sale or purchase of a child, which is a third degree felony, reports KIII . They are extremely distraught about this incident, especially the boy's father.

    Finalement, il devrait attendre septembre pour présenter son plan pauvreté — Macron

    La misère n'attend pas et on va perdre une année", a commenté dans Le Monde Véronique Fayet, la présidente du Secours catholique. Emmanuel Macron avait en effet promis début juin de se rendre en Russie en cas de demi-finale de la France à la Coupe du monde .
    Les NTIC : avantages et inconvénients

    Les NTIC : avantages et inconvénients

    En effet, avoir mille et une tâches à accomplir à la fois, ça peut avoir des effets négatifs. En effet, les travailleurs effectuent les tâches beaucoup plus rapidement tout en conservant leur qualité de vie.
  • Michael Avenatti Floats 2020 Bid For President

    Michael Avenatti Floats 2020 Bid For President

    After tweeting that "only a street fighter has a chance at displacing the 'King, '" Avenatti was asked when he would announce a 2020 run.
    Horner: Mercedes' apology to Hamilton was 'bizarre'

    Horner: Mercedes' apology to Hamilton was 'bizarre'

    The second Red Bull of Daniel Ricciardo who was running in second place at one point, had to retire with a gearbox issue. I can't predict what will happen but that's not getting in my way'.
    Jeune tué lors d'un contrôle policier : nouvelle nuit de violences à Nantes

    Jeune tué lors d'un contrôle policier : nouvelle nuit de violences à Nantes

    L'avocat des proches de la victime devrait prendre la parole à l'issue de la marche blanche pour évoquer le fond du dossier. Les pompiers étaient encore en intervention pour éteindre les flammes vers 3h00.
  • "Wikipedia" has suspended the work of four European languages

    They've heard the massive opposition, including Internet blackouts and 750,000 people petitioning them against these proposals. On Wednesday, Wikipedia shut down in Spain, Italy and Poland to protest the reforms, but access was restored Thursday.

    Thanos-Inspired Subreddit Poised to Ban Half its Members

    The admins are designing a bot for me that will allow me to do the job in a quick and easy manner. Granted, with what happened in Infinity War , that might not help.
    Greenpeace activists crash drone, toy plane into French nuclear plant

    Greenpeace activists crash drone, toy plane into French nuclear plant

    France derives about 75 percent of its electricity from 19 state-controlled plants, according to the World Nuclear Association .
  • Neymar joins Messi and Ronaldo in Kazan mural club

    Neymar joins Messi and Ronaldo in Kazan mural club

    Sweden will be tough opponents, though, as they have shown throughout the tournament they are capable of shutting teams out. Gareth Southgate's England side face Sweden in Samara on Saturday. "During my time with England we met them four times".
    Jawad Bendaoud interpellé après avoir insulté des policiers — Seine-Saint-Denis

    Jawad Bendaoud interpellé après avoir insulté des policiers — Seine-Saint-Denis

    Lors de son interpellation, il aurait demandé à des personnes présentes sur les lieux de le libérer, sans succès. En février dernier, Jawad Bendaoud a été relaxé des faits de "recel de malfaiteurs terroristes ".

    Les roulades de Neymar inspirent les internautes — Mondial

    Au total, le Brésilien aura donc passé 13 minutes et 50 secondes de jeu au sol depuis le début du tournoi. Lire aussi Coupe du monde 2018: le Mondial du PSG! .


Populaire

Comment devenir webmaster?
Il est amené à rajouter des textes, des images, des vidéos. Il procède également à l’analyse du trafic.

Protesters, Police clash at West Bank village slated for demolition
In one video , Israeli forces were seen violently dragging a Palestinian woman on the ground and pulling off her headscarf. Khan al-Ahmar is mainly made up of makeshift tin and wood structures, as is traditionally the case with Bedouin villages.

Qui est Angela Ponce, la candidate transgenre qui représentera l’Espagne — Miss Univers
Angela Ponce , 26 ans, a remporté ce week-end l'élection de Miss Univers Espagne , qui la qualifie pour l'ultime étape. Une publication partagée par ANGELA PONCE (@angelaponceofficial) le 2 Juil.

Willian unfazed by Barcelona rumours
Willian made 55 appearances in all competitions for Chelsea FC last season, scoring 13 goals. Indeed, the Blues turned down a £50million offer from Barcelona for the Brazilian recently.

Mondial 2018 : ils ratent leur penalty, deux joueurs colombiens menacés de mort
Sur les réseaux sociaux notamment, les insultes et les menaces de mort à l'encontre des deux joueurs ont fleuri: " Meurs Carlos Bacca ".

Steph Curry Announced Some Major Personal News On Instagram
Steph Curry went to Davidson College before leaving his senior year for the National Basketball Association draft. Jack Curry and he was born a few weeks before Ayesha was due, surprising the family.

Wellington baristas welcome research showing drinking coffee is linked to longer life
Coffee beans are rich in polyphenols; they contain higher concentrations of these antioxidants than blackberries or kale. Despite that, she also said the results reinforce previous research and add additional reassurance for coffee drinkers.

Entre Airbus et Boeing, la guerre fait rage
Le management, président et CEO, restera brésilien mais rapportera directement à Dennis Muilenburg, le président du groupe Boeing. Pour Embraer, l'opération permettra de bénéficier de la force de frappe commerciale de Boeing.

Here's is what to expect from Reliance Industries Ltd’s AGM today
The price and plans for both the services haven't been announced yet and should be made available closer to August 15th. Shares in rival Indian firms that offer home broadband services fell after Reliance unveiled JioGigaFiber .

Votre voiture doit être dans un état impeccable
En ce qui concerne la sécurité, le choix des pneus parfaitement adaptés est extrêmement. Mais tout d’abord, vous devez savoir où trouver les pièces compatibles avec votre voiture.

Tendances