New drug discovery will soon let you eat anything without gaining weight

08 Décembre, 2018, 21:55 | Auteur: Yves Courtet
  • Turning Off One Gene May Allow You to Eat Without Gaining Weight Scientists Say

An global team of researchers has reportedly hit a new gene breakthrough that may lead to the development of anti-obesity pills.

An worldwide team of researchers found that when they removed a single gene known as RCAN1 from mice and fed those mice a high fat diet they didn't gain weight like the mice who still had the gene.

According to research, the weight loss market in the United States alone is already worth around $66 billion Dollars.

The global team, led by scientists at the University of Texas Southwestern Medical Center and Professor Damien Keating at Flinders University, are hopeful a similar approach that inhibits this gene will also be effective with humans to combat obesity and serious diseases like diabetes. However, the estimated number of dieters may be decreasing due to the acceptance of obesity and the body positivity movement.

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Reporting in the journal EMBO Reports, scientists at the University of Texas Southwestern Medical Center and Flinders Unversity in Australia found that the single gene, known as RCAN1, acts as a feedback inhibitor for all kinds of metabolic processes and the production of body heat.

The study used a large genetic screen in rodents to identify novel genetic candidates that may cause obesity, potentially paving the way for new drug therapies. The time duration for the diets were from eight weeks to up to six months. Part of the mechanism for this involves the transformation of energy-storing "white fat" into energy-burning "brown fat", which cuts down on weight gain. The process continues even if the mice were resting. The new pill will target this gene and hence help people control their weight. This mainly prevents these cells from causing neurodegenerative disorders like Alzheimer's disease.

Will this new drug be the weight-loss elixir we have been looking for? "It means the body would store less fat without the need for a person to reduce food consumption or exercise more".

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