Already, significant impacts have been felt through the mid-Mississippi Valley, where some 800 motorists were stranded during Friday's evening commute in St. Louis, Missouri.
The National Weather Service issued winter weather advisories for Missouri, as well as IL and Indiana.
The University of Missouri men's basketball game at the University of SC was also canceled Saturday because of weather-related travel problems, the team tweeted.
Those who must travel are being urged to carry a winter storm survival kit in case of emergency. The National Weather Center said 17 inches of snow has fallen in central Missouri.
Large sections of Missouri, Illinois and IN are under winter weather advisories, and hazardous travel conditions are expected through most of the weekend.
The storm moved into Kansas and Nebraska from the Rockies on Friday, then east into Missouri, Iowa, Illinois and IN, covering roads and making driving risky. It would be the most snow a single storm has dumped on the city since 2014 when a January blizzard left 10.8 inches.
Sally Johnson, a meteorologist in St. Louis, says the storm has the potential to drop the most snow in five or six years. It would be among the city's 10 greatest snowstorms - landing at the No. 2 spot - of all time if that happens. It says locally higher amounts of snowfall are possible.
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There, he met with a roommate, "and really didn't show any signs that he had just been involved in this incident", Pytel said. Firefighters at a nearby station provided immediate medical help before Corona was rushed to the UC Davis Medical Center.
Travel may be treacherous along Interstate 70 from the Kansas City area to St. Louis and along I-64 from St. Louis to Louisville, Kentucky.
"In much of swath from Missouri to southern OH, this will heavy and wet and a strain to shovel", AccuWeather meteorologist Bill Deger wrote in a blog post.
A few major East Coast cities are likely to see some impact, including Washington, Baltimore and Philadelphia, and there is a possibility for light accumulation in NY along the northern edge of the storm.
Snow is forecast for the Appalachian Mountains and the mid-Atlantic on Saturday evening and Sunday. Four to 6 inches are predicted for Washington and 2 to 3 inches for Baltimore, they said.
Bands of icy rain are forecast for areas farther south, including parts of Virginia and SC.
Gia, which is what The Weather Channel is calling it, should produce heavy snow and some ice accumulation in the Rockies and more than 1,000 miles eastward to Philadelphia and New Jersey.
There is a small chance that the southern Appalachians get enough freezing rain and sleet to turn into an ice event Saturday into Sunday. The Southeast has seen abundant precipitation in December and January, and the additional rain could put a strain on already-high rivers.
Solari also brushed aside questions over Isco , who has fallen out of favour at the club and been linked with a move away. Players who reach the Primera Division, play here for many years, and have won a lot, they know what they need to do".
He said their apartments and workplaces were searched, adding that the Polish suspect had worked "for several state institutions". Huawei is a leader in the development of next-generation "5G" mobile networks and a key player in building them in Europe.
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