The lovable grump, with her permanently "frowning" face, became an internet sensation at just 5 months old, when a photo of her was posted on Reddit back in 2012.
Grumpy Cat's family, including her owner TabathaBundesen, made the announcement of her passing this morning on Twitter and described her as their "baby".
The internet star now has millions of followers on social media.
Grumpy Cat - real name Tardar Sauce - shot to fame as a figurehead of online culture thanks to her permanent frown apparently signalling displeasure at anything and everything.
Trump says 'I hope not' about getting into war with Iran
He reportedly is frustrated at suggestions that advisers, led by national security adviser John Bolton are pushing him to war. This was President Obama's signature diplomatic achievement and took cooperation with the UN Security Council to pull it off.
Nick Kyrgios melts down at Italian Open, throws chair
The Swiss was more aggressive and he efficiently defended the second serve before seizing the only chance on the return he got. He's a champion of the sport, one of the greatest we'll ever see, I think he will pass Federer [in terms of grand slam wins].
Plane crash near Dubai airport: people killed
Dubai International Airport is the world's busiest when measured by international passenger traffic. The victims include three United Kingdom nationals and a South African, GCAA said in a statement .
"Though I suppose there could be a different father, promiscuous cats you know", Grumpy Cat's website stated.
"We are unimaginably heartbroken to announce the loss of our beloved Grumpy Cat", her owners wrote.
Her popularity was sealed by her participation at the South by Southwest Interactive (SXSW) festival in Austin, Texas. It's unclear if her genetic quirks played a role in her somewhat early death, but it's worth noting that research on domestic cats suggests the average lifespan of a house cat is anywhere from 13 to 17 years. Importantly, the cat wasn't actually that angry; her scowl was the unique result of feline dwarfism and an underbite.
Grumpy Cat wasn't always Grumpy Cat.
But that did not stop the cat from putting smiles across the faces of millions of people. The following year, she scored her own Lifetime holiday movie, "Grumpy Cat's Worst Christmas Ever", a two-hour spectacle featuring the voice talents of actress Aubrey Plaza as the title character.
The four-time Italian Open victor next plays Argentine seventh seed Juan Martin Del Potro for a place in the semi-finals. Federer, who had been set to take on Stefanos Tsitsipas in the quarterfinals, bowed out with an injury to his right leg.
The nearest competitor after Lee is Tommy Fleetwood of England, who is four strokes back of Koepka at three under par. Open champion, could also become the reigning two-time PGA Championship victor with a victory at Bethpage.
According to sources , Pattinson is all set to play Batman in Warner Bros' next, The Batman , directed by Matt Reeves . Already petitions have been launched calling for Pattinson to be replaced before he's even been officially cast .
The vote allows same-sex couples full legal marriage rights, including in areas such as taxes, insurance and child custody. Tsai said earlier that she recognised the issue had divided "families, generations and even inside religious groups".
But Katy has the support of her longtime boyfriend, KO Kelly (Zane Holtz), who has his own dream of becoming a professional boxer. Even though a security guard tries to stop her, she proceeds to go down to a basement where Wayne's suit is in a glass case.
At one point during the criminal proceedings against Lord Black, Trump offered to testify on Black's behalf in court. Trump Restaurants LLC earned roughly $4.3 million in 2018, which is up about a half million dollars from 2017.
William Hill has since removed the ad and is in the process of conducting a full review of existing content on the platform. But the Advertising Standards Authority (ASA ) said it must not appear again in its current form.
Others have argued that older Australians would be most affected by tax reform proposals that have dominated much of the campaign. He had been actively supporting Labor's campaign for elections on Saturday after six years in opposition.
US F-16 fighter jet crashes in California
The F-16 was assigned to the Air National Guard , a federal military reserve force under the Air Force, officials said. Thomas McNamara, vice commander of the Air Force Reserve's 452nd Air Mobility Wing, said at a news conference Friday.
China formally arrests Canadian ex-diplomat, businessman
Public Safety Minister Ralph Goodale said Canadians thinking of travelling to China should consult with Global Affairs Canada. Another Canadian held in China, Robert Schellenberg, was re-sentenced to death in a drug case following Meng's detention.