Sir Peter Ratcliffe awarded joint Nobel Prize for Physiology or Medicine

09 Octobre, 2019, 13:40 | Auteur: Anatole Charbonneau
  • Peter J. Ratcliffe William G. Kaelin Jr. and Gregg L. Semenza

He then noticed the caller ID was from Europe, "And at that point my heart started racing", the 61-year-old told AFP in an interview. These discoveries pave the way for new ways to fight anaemia, cancer and other diseases.

Ratcliffe received the prize alongside fellow researchers William Kaelin Jr. and Gregg Semenza, for their work demonstrating how human cells respond to changing oxygen levels.

'The seminal discoveries by this year's Nobel Laureates revealed the mechanism for one of life's most essential adaptive processes.

Semenza, on the other hand, missed the very first pre-dawn call in the academy, also waited a few anxious minutes from the telephone, answering it next time around. "I was in a daze", he said, adding he had not been expecting the honor but had since celebrated with champagne.

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In the center of the trio's study is the way your system registers and reacts to oxygen, that supports life as we know it on Earth. Scientists have long known that climbing to high altitudes spurs production of the hormone erythropoietin, which in turn leads to more red blood cells, to help compensate for lower oxygen levels. Kaelin came to the same subject from a different direction, through his investigations into von Hippel-Lindau's disease. "The three scientists did not directly collaborate, but read each others" papers and met and shared ideas at conferences. China accepted this type of medication for anemia this past year.

For Kaelin, the breakthrough emphasized the significance of fundamental research - which is, work aimed at broadening understanding of natural phenomena and driven with scientists' fascination. "Here I am as a cancer biologist helping to contribute to a new drug for hematological condition, namely anemia", he said, adding he hoped to use his voice to advocate for sufficient funding for such science.

"After she died, he believed winning the Nobel" will just be overly bittersweet and it'd be too devastating" he stated,"but I am at a stage today where I'd like to believe she is grinning down and nodding and saying'I told you, I told you that this sometimes happens.



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