Scientists discover protein that mimics effects of exercise

14 Janvier, 2020, 17:05 | Auteur: Yves Courtet

"The flies without Sestrin did not improve with exercise", said Professor Jun Hee Lee, from MI. The findings could eventually help scientists combat muscle wasting due to aging and other causes. Kim, working with professor Jun Hee Lee, Ph.D. and a team of researchers wanted to know more about the protein's apparent link to exercise. Next, they encouraged their samples, a bunch of Drosophila flies to work out by developing a small treadmill for them.

"Researchers have previously observed that Sestrin accumulates in muscle following exercise", said Myungjin Kim, a research assistant professor at the University of MI in the US.

Taking advantage of Drosophila flies' normal instinct to climb up and out of a test tube, their collaborators from Wayne State University in the U.S. developed a type of fly treadmill. Scientists from the University of MI therefore wanted to see if artificially upping an animal's Sestrin levels could produce the beneficial effects that are associated with the protein.

When they compared the results from both fly batches, they found that the normal flies' ability to run around improved over a period by four to six hours, while the flies without Sestrin did not make any progress without exercise.

Australian Ormsby secures Hong Kong Open title
Lowry made birdies at the second, fourth, ninth, 16th and 17th and dropped just one shot by three-putting from long range at the seventh.

Marcus Stoinis slams highest-ever individual score in BBL history
Records are tumbling at the MCG, with Melbourne Stars allrounder Marcus Stoinis' blasting the highest score in BBL history. The star of the game was undoubtedly Stars' opener batsman Marcus Stoinis , who played a superb unbeaten knock of 147.

Oscars 2020: A List Of Snubs, Topped By Jennifer Lopez
Fans of Joker will definitely be pleased with the list, as the movie netted itself 11 nominations. 1917 and Once Upon a Time ... Following the results of this year's selection, the United Kingdom academy announced it would be reviewing its voting process.

When mice that were bred to lack Sestrin exercised, there were none of the expected improvements in aerobic capacity, respiration, and the ability to burn fat. "The flies without Sestrin did not improve with exercise".

"Flies can usually run around four to six hours at this point and the normal flies' abilities improved over that period". In fact, flies with overexpressed Sestrin didn't develop more endurance when exercised.

Flies with overexpressed Sestrin didn't develop more endurance when exercised. Prof. Myungjin Kim. "This kind of combined effect is important for producing exercise's effects". "This independent study again highlights that Sestrin alone is sufficient to produce many benefits of physical movement and exercise", says Lee.

The scientists are now further exploring the manner in which Sestrin is produced within the body, and are looking into the development of supplements containing the protein. In short, Sestrin could lead to a treatment for people who cannot exercise and help them stay healthy.

Conseillé:

  • England, South Africa eye series win

    England, South Africa eye series win

    The third test at St George's Park is followed by the last at the Wanderers in Johannesburg from Jan 24-28. Keegan Petersen, who was added as cover ahead of the Newlands Test, misses out.
    Why the Government of National Accord in Libya is illegitimate

    Why the Government of National Accord in Libya is illegitimate

    The most famous paramilitary organization that is part of the National Security Service of GNA is the «RADA» group. He is one of the main opponents of the Muslim Brotherhood in the region and one of the most famous fighters against terrorism.
    Les NTIC : avantages et inconvénients

    Les NTIC : avantages et inconvénients

    En effet, avoir mille et une tâches à accomplir à la fois, ça peut avoir des effets négatifs. En effet, les travailleurs effectuent les tâches beaucoup plus rapidement tout en conservant leur qualité de vie.
  • Corruption scandals in the Israeli Genesis Prize

    Corruption scandals in the Israeli Genesis Prize

    The prosecutor José Grinda, however, insisted on his maintaining the ‘accused’ status. Mikhail Fridman has a legal case on his hands as well.
    AB on Proteas comeback: 'I'd love to'

    AB on Proteas comeback: 'I'd love to'

    Now, with the T20 World Cup in less than ten months, plans seem to be in place to facilitate his return. The right-handed batsman had announced his retirement from global cricket in 2018 owing to workload.

    Votre voiture doit être dans un état impeccable

    En ce qui concerne la sécurité, le choix des pneus parfaitement adaptés est extrêmement. Mais tout d’abord, vous devez savoir où trouver les pièces compatibles avec votre voiture.
  • Arsenal manager Mikel Arteta hints on another loan move for Eddie Nketiah

    Arsenal manager Mikel Arteta hints on another loan move for Eddie Nketiah

    Arteta has been looking at potential options and may use his agency connections in order to take on Stones, according to the Sun . The England worldwide has struggled for game time this season owing to his injury and subsequent loss of form.
    Bruno Fernandes: Man Utd in talks with Sporting Lisbon over midfielder

    Bruno Fernandes: Man Utd in talks with Sporting Lisbon over midfielder

    Midfielder Fernandes, 25, scored twice as Sporting beat Vitoria Setubal 3-1 in the Portuguese top flight on Saturday. They were not impressed with any of United's suggestions, which is what is holding up the deal.

    "Amiens, une équipe de peintres" — Christophe Galtier (Lille)

    On a souffert, mais l'équipe a fait preuve de beaucoup d'abnégation, et elle a su marquer et conserver son avantage. De quoi exaspérer Christophe Galtier qui a laissé éclater sa frustration dans le vestiaire du stade Gaston-Gérard.
  • Harmanpreet Kaur To Captain India In Women's T20 World Cup

    Harmanpreet Kaur To Captain India In Women's T20 World Cup

    The Ladies in Blue will kick-off their marketing campaign on the showpiece occasion towards hosts Australia in Sydney on February 21.
    'Westworld' Season 3 Premiere Date Set for March

    'Westworld' Season 3 Premiere Date Set for March

    We know surprisingly little about Westworld season 3 , and that's despite there being three trailers already available to watch. What we want most from Season 3 are answers about that Season 2 post-credits scene about the Man in Black ( Ed Harris ).
    Leroy Merlin en Russie est au bord du scandale ?

    Leroy Merlin en Russie est au bord du scandale ?

    La part du réseau Leroy Merlin sur le marché russe de "l'équipement ménager" approche les 20%. Beaucoup d'entre eux se plaignent des manifestations de corruption et des violations de l'éthique des affaires.


Populaire

The craziest victory in Chiefs playoff history keeps hope alive — SportsBeat KC
Lambeau Field has never been a happy hunting ground for Seattle, who have now lost nine in a row in the Packers' home stadium. In his first season with the Green Bay Packers, Adrian Amos has proven to be a pivotal piece of the team's revamped defense.

Bumrah set to receive Polly Umrigar Award
BCCI Secretary said: "The BCCI Awards are an important feature in the Indian cricket calendar, a mix of ambition and inspiration". Legspinner Poonam Yadav will take the top prize in women's category and will be awarded the best global woman cricketer women.

Oldest stuff on Earth found inside meteorite that hit Australia
To date the material, the researchers used a unique technique to measure the effects of cosmic rays hitting the grains. Last year, researchers found a new mineral from the Wedderburn meteorite that was found in Australia 70 years ago.

No More 'Wear a Tie' Resolutions for Zuckerberg
In addition to being the largest social media platform in the world, Facebook, a huge ecosystem for news and advertising, continues to react with its new advertising policy.

Joaquin Phoenix arrêté lors d'une manifestation pour le climat à Washington
Jane Fonda , qui a été interpellée par la police à de nombreuses reprises, collabore régulièrement avec des organisations telles que Greenpeace.

Sania returns to match after two years, wins Hobart International tournament
After clinching the win, Sania Mirza shared an adorable picture with her son, in which she can be seen giving a high-five to him. In 2013, she retired from the individual competition after becoming the most successful tennis player in India ever.

Britain, France and Germany trigger dispute mechanism over Iran nuclear deal
Under the agreement, worldwide sanctions against Iran were lifted in return for Tehran agreeing to curb its nuclear programme. The existing accord was signed in 2015 between Iran and Russia, China, France, the United Kingdom and the USA plus Germany.

Verified videos show plane in Iran struck before fiery crash
Chilling footage has recorded the moment the Ukraine International Airlines Flight 752 crashed outside of Tehran on Wednesday . The crash came just hours after Iran carried out missile strikes on two airbases housing United States forces in Iraq.

Ski: Armand Marchant a abandonné à Adelboden - Édition digitale de Bruxelles
Victor Muffat-Jeandet termine 5e, Alexis Pinturault 8e, Jean-Baptiste Grange 15e et Julien Lizeroux 25e. Le Valaisan vient de remporter (pour la deuxième fois) le slalom de Madonna di Campiglio.

JPMorgan Could Launch CME Bitcoin Options Soon
Given the dominance of CME in trading Bitcoin futures on regulated exchanges, this new offering may change things, they said . When ICE debuted its physically settled futures contracts, Bakkt in September the prices fell that time too.