The bowler conceded 17 runs but recovered to end with 2 for 28, in the end playing a pivotal role in restricting Ireland to 208 for 7.
However, the home side appeared comfortably on course for victory - bringing up their hundred inside 10 overs with just two wickets down - until the game was decided in the last over.
Ireland's 20-year-old left-arm fast bowler Josh Little had ball in hand and, taking two wickets, managed to see out the final ball win.
Rutherford and Dwayne Bravo - making his first global appearance since 2016 - fell to impressive left-arm seamer Josh Little (3-29) in the final over as Ireland bounced back from defeat in the recent ODI series to take a 1-0 lead in the three-match rubber.
With five needed from the final delivery of the game, Hayden Walsh Jr missed a desperate swing, leaving the Irish to celebrate their first win of the tour.
"Everyone is in ecstasy, we came so close in this second ODI (lost by a wicket) and it may have affected us in this third ODI, so to show the bottle and come out against one of the best teams T20 cricket and getting a win was great for the team atmosphere, "said Irish skipper Andrew Balbirnie".
Bravo's first three balls on his return were dispatched for 16 as Stirling clipped him for four and then smashed successive sixes down the ground.
Stirling would fall just 5-runs short of his century, but his 95 would prove more than useful and included no fewer than 8 sixes and half a dozen fours.
West Indian captainKieron Pollard hit a windy 31 of 15 balls, threatening to withdraw the match from Ireland.
Stirling smashed eight sixes and six fours in a brutal display of hitting as he and opening partner Kevin O'Brien (48 off 32) took Ireland to 154-0 after 12.1 overs, clubbing a world-record powerplay score of 93 in the process.
But Sherfane Rutherford (26 of 13) and Nicholas Pooran (26 of 23) marlled 18 of Barry McCarthy by 27, throwing three six and two four between them to leave the West Indies needing 16 of 12 balls.
"It was touch and go, but we're enjoying the tight games - we came out the right side this time, so it's a nice feeling".
Watch the second T20I between West Indies and Ireland, in St Kitts and Nevis, live on Sky Sports Cricket from 9.45pm on Saturday.
Leg-spinner Walsh took 1-25, his sole victim being Stirling caught at deep-midwicket going for the big shot which would have brought him a century.
But the hosts must now win Saturday's second T20I, in Basseterre, to take the series to a decider at the same venue on Sunday.
La police anti-émeute a utilisé des canons à eaux et tiré des volées de gaz lacrymogènes pour les disperser. Et Hassan Diab, désigné comme son successeur le 19 décembre, n'a toujours pas formé d'équipe.
Bloomberg needs extra time to collect his financial information and to view and complete and submit his report, "lawyer H. However, due to the complexity of his companies and the need to obtain certain information from third parties, Mr.
The Atlanta Hawks are acquiring Minnesota Timberwolves point guard Jeff Teague in a three-player trade, league sources told ESPN . Teague and Graham are being given fresh starts and it will be interesting to see how they fare in their debuts with the Hawks.
He will open up with Jan-Lennard Struff, and the other seeds in his section don't pose too much of a threat until the quarters. Former Grand Slam finalist Milos Raonic and last year's quarterfinalist here, Roberto Bautista Agut , await in the wings.
He also allegedly subjected her to long and frequent exams that were unnecessary for her treatment, she said. "I knew I was being assaulted", but "I just kind of froze like a deer in headlights", she adds.
Lire la suiteLivre: 911 by Porsche (Glénat)Edwin Baaske est né en 1962 à Hambourg, soit un an avant la Porsche 911. Ces jantes sont chaussées de pneus 235/35 ZR 20 à l'avant et de 265/35 ZR 20 à l'arrière.
An exclusive from The Sun claims that talks with Fernandes have actually stalled due to a dispute over bonus payments. Add-ons which have (supposedly) been proposed by Ed Woodward surrounds Fernandes winning the Ballon d'Or.
Si vous possédez ce gobelet de voyage, ne l'utilisez plus et rendez-le dans un magasin IKEA pour remboursement. Des tests récents font état d'un risque de migration chimique à des niveaux supérieurs aux limites autorisées.
The 19-year-old replaced Lukasz Piszczek on 56 minutes with Dortmund 3-1 down and had reduced the deficit three minutes later. Dortmund are fourth in the table, four points behind leaders RB Leipzig , who play later on Saturday.
Watch Camila Cabello defend 2019 against James Corden
The late night host eventually admitted defeat and joined Cabello for a rendition of her duet with Mendes, "Senorita". Corden , meanwhile, presents "Livin 'La Vida Loca" by Ricky Martin and " Smooth " by Santana as a counterpoint.
Mac Miller: 'Circles' Album Stream & Download
Eminem, Mac Miller , Tech N9ne, Moxas, PFV, AK, and a handful of others that are slipping my mind right now". Posthumous album from Mac Miller , circles , dropped on January 17 and fans reflect on the thoughtful tracks.
Yemen: 23 rebels killed in army preemptive action
Saudi state television reported as many as 60 military personnel were killed in the attack, with dozens more wounded. Al Ekhbariya cited sources that the attack was carried out using ballistic missiles and drones.
Space Force Offers First Peek at Camouflage Uniform
IT'S CAMO! The standard green, brown and black shades of camo are the LEAST camouflaged colors on a space ship or in space. US Vice President Mike Pence noted that the idea of creating a space force has been discussed since the 1950s.