Oxford coronavirus vaccine trial results "extremely encouraging", United Kingdom government says

21 Juillet, 2020, 09:24 | Auteur: Anatole Charbonneau
  • Coronavirus vaccine trial First tested in US yielded antibodies in patients researchers say

We don't know exactly know what protects us against a coronavirus infection, as there is still so much we don't know, so our research continues.

"This is very positive news".

The vaccine, named AZD1222 and being produced by pharmaceutical corporation AstraZeneca and researchers at Britain's College of Oxford, did not prompt any severe aspect effects and elicited antibody and T-mobile immune responses, in accordance to trial benefits posted in The Lancet health care journal.

Second, within 28 days, it provoked an antibody response.

US drug maker Pfizer and its German partner BioNTech also reported positive progress Monday on their vaccine candidate.

What do all these studies mean?

According to a phase one/phase two study of more than 1,000 patients, the vaccine triggered two immune responses: an increase in antibodies and a T-cell response.

Dr Adrian Hill, director of the Jenner Institute at Oxford University, said the immune response in was "good in nearly everybody".

The trial carried out on 60 adults in Germany proved to be safe and successfully induced an immune response.

This vaccine is being developed by the University of Oxford in partnership with AstraZeneca.

Depending on the study outcomes and if the data is encouraging and the vaccine is found to be effective during the trials, it could take a total of seven months for the trials to be completed and for the vaccine to be launched, he added. The university's researchers noted that some recipients may get protection from just one dose, and that ultimately the data may show that the majority of people are protected by a single shot. Moderna's vaccine also uses a messenger RNA platform. Here, no attenuated viruses are injected.

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"Overall, the results of both trials are broadly similar and promising", Naor Bar-Zeev and William Moss, two vaccine experts from Johns Hopkins Bloomberg School of Public Health, wrote in a commentary in The Lancet.

What are the next challenges next?

In SARS-CoV-2, antibodies are known to fade between three-six months, as reported by various studies, he said. "Sometimes, that correlates with protection in vaccines".

In the United States there are hopes of a potential coronavirus vaccine being developed by U.S. pharmaceutical firm Moderna.

AstraZeneca's is among the the foremost vaccine candidates against a pandemic that has claimed extra than 600,000 life, together with others in mid and late-phase trials.

The vaccine is one of the farthest along for Covid-19. The company had last week started clinical trials of its COVID-19 vaccine candidate with the first human dosing.

Early data from these trials has been shared with the University of Oxford.

Panacea Biotec in June said that it was setting up a joint venture firm in Ireland with US-based Refana Inc to develop a vaccine for COVID-19.

The UK has already struck a deal to acquire 100 million doses of the prospective vaccine.

Indian Immunologicals, a subsidiary of National Dairy Development Board (NDDB), has inked an agreement with Australia's Griffith University to develop a vaccine for coronavirus.

"We would like to do better, and we are all working to get to those better vaccines", Moody said, "but having something effective soon is the top priority".



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