AstraZeneca's U.S. trial could remain on hold

15 Septembre, 2020, 10:53 | Auteur: Yves Courtet

Scientists say that a pause is not uncommon in large trials, and that a speedy resumption of testing was expected. "I still don't see a proper plan on paper to do that [in India] beyond 400 million doses.you don't want a situation with the vaccine where you have capacity for your country but you can't consume it", he told the paper. "Hopefully they'll work it out and be able to proceed along with the remainder of the trial".

Oxford said that globally some 18,000 people have received its vaccine so far.

Last week, the Oxford vaccine candidate from Astra Zeneca halted human trials when a volunteer fell ill in the United Kingdom, after which the Serum Institute of India also stopped trials - citing a show-cause notice issued form the Drug Controller of India.

The British adverse event involved a study patient thought to be suffering a rare spinal inflammatory disorder called transverse myelitis. But these trials have already resumed in Britain.

The university insisted that it was "committed to the safety of our participants and the highest standards of conduct in our studies and will continue to monitor safety closely".

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Pauses in drug trials are commonplace but the temporary hold led to a sharp fall in AstraZeneca's share price following the announcement Tuesday. But he said he decided not to accept government funding for vaccine development to shield the pharmaceutical giant from politics.

The coronavirus vaccine could be administered via an inhaler, after Imperial College London launched a trial to test the effectiveness of delivering a candidate directly into the lungs.

Fox News medical contributor Dr. Marc Siegel said Monday that the common flu, unlike coronavirus, is a "moving target" that often changes form from year to year, while COVID-19 is more static.

Coronavirus vaccines being developed in China may be ready for use by the general public as early as November, an official with the Chinese Center for Disease Control and Prevention (CDC) said. The World Health Organization (WHO) had flagged AstraZeneca's as the most promising.

"Science is at work to give the world efficient and secure treatments and vaccines", he said.

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