Convalescent plasma shows little benefit in Covid-19 hospitalised patients

26 Novembre, 2020, 14:35 | Auteur: Yves Courtet
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The mortality rate was almost the same at 11per cent in the convalescent plasma group and 11.4 per cent in the placebo group, a difference not deemed statistically significant. In 30 days, researchers did not see any differences in the symptoms and health of patients, with the mortality rate remaining unchanged at 11 per cent in the group who received plasma, and 11.4 per cent among the placebo group.

"Convalescent plasma - write the authors of the publication, researchers of the Italian Hospital of Buenos Aires - is frequently administered to patients with Covid-19 and has been reported, largely on the basis of observational data, to improve clinical outcomes". The top health research body has also stated that the experimental therapy did not reduce death risk in patients.

The study was published in The New England Journal of Medicine.

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A study conducted in India in October revealed that plasma therapy helped in evening out symptoms among COVID-19 patients who were experiencing shortness of breath and fatigue.

"This finding is in contrast to the findings of a series of non-randomised studies claiming convalescent plasma to be of substantial benefit and illustrates the importance of randomised, controlled trials, especially in the context of a pandemic", they added. "This must stop. Families are unnecessarily put under pressure to arrange for donors", said a public health activist.

Recently, ICMR issued a standard operating procedure for plasma therapy and advised states to desist from its indiscriminate use.

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