Médicaments à éviter: la revue Prescrire publie sa 9e liste noire

29 Novembre, 2020, 09:28 | Auteur: Yves Courtet
  • Au total 93 médicaments sur les 112 épinglés sont commercialisés en France

La liste 2021 porte sur 112 médicaments dont 93 commercialisés en France, explique Prescrire. Jeudi 26 novembre 2020, elle a publié un bilan " des médicaments à écarter pour mieux soigner ".

⇒ A cause d'une évaluation de la balance bénéfices-risques en cours par Prescrire: le nintédanib (Ofev® en pneumologie, Vargatef® en cancérologie), "un inhibiteur de tyrosine kinases avec effet antiangiogenèse." . Pour être commercialisé, un médicament doit avoir une balance positive: ses bénéfices doivent être supérieurs aux risques encourus.

Trois autres médicaments sont pointés, qui ont une certaine efficacité, mais avec des effets indésirables disproportionnés ou pour lesquels existent d'autres options moins dangereuses. Les médicaments figurant dans cette liste sont "des causes de mortalité, d'hospitalisations ou d'effets nocifs graves ou très gênants, largement évitables", selon la revue Prescrire.

UK police arrest over 60 in anti-lockdown protests
Anti-lockdown protests have been repeatedly held in the United Kingdom since the start of the coronavirus pandemic. The force said: "These were for a number of different offences, including breaching coronavirus restrictions".

49ers may need temporary home because of new COVID-19 rules
SANTA CLARA, Calif. - For at least the next three weeks, the San Francisco 49ers are a team without a home. San Jose State, meanwhile, have home games on December 5 against Hawaii and December 11 against Nevada.

Pièces détachées et caractéristiques automobiles qui entrent dans l’histoire
Un son merveilleux, de magnifiques systèmes et voitures ont même fait de la place pour vos CD. Cependant, les écrans tactiles ne sont pas encore totalement fiables.

Cette balance est réévaluée au regard de nouveaux médicaments disponibles sur le marché. C'est le cas du fameux médicament contre la chute modérée de cheveux chez les hommes, le "finastéride 1 mg" (Propecia et génériques).

"Les effets indésirables auxquels ils exposent sont disproportionnés par rapport à leur faible efficacité ou à la bénignité de la situation clinique dans laquelle ils sont autorisés", indique Prescrire. Un autre médicament déconseillé est le Nootropyl, un traitement utilisé contre les troubles cognitifs liés au vieillissement. Il s'agit d'eskétamine (Spravato) en spray nasal "d'efficacité très incertaine" contre la dépression résistante aux antidépresseurs; pimécrolimus (Elidel non commercialisé en France) contre l'eczéma atopique, mais avec un risque accru de cancer de la peau et de lymphome. La revue précise que la balance bénéfices-risques du nintédanib reste défavorable dans d'autres situations dans lesquelles il est autorisé: la fibrose pulmonaire idiopathique pour Ofev® (n° 389 p. 180); certains cancers bronchiques non à petites cellules sous le nom Vargatef®. Cette liste recense des médicaments plus dangereux qu'utiles, à écarter des soins.

Enfin, une dizaine de médicaments de la famille des gliflozines, contre le diabète, figurent aussi parmi les médicaments à écarter. Néanmoins, que les patients se rassurent: " ces médicaments ne sont pas forcément de futurs "Mediator", au centre d'un scandale et de procès impliquant une firme et l'Agence française du médicament.

Conseillé:

  • Zayn Malik gives newborn daughter's first Thanksgiving a miss with Gigi?

    Zayn Malik gives newborn daughter's first Thanksgiving a miss with Gigi?

    Nonetheless, it looks like Gigi and family celebrated Thanksgiving in a very cozy, intimate setting and fans are loving it! She captioned the photo, "Mamma's".
    Leroy Merlin en Russie est au bord du scandale ?

    Leroy Merlin en Russie est au bord du scandale ?

    La part du réseau Leroy Merlin sur le marché russe de "l'équipement ménager" approche les 20%. Beaucoup d'entre eux se plaignent des manifestations de corruption et des violations de l'éthique des affaires.

    Fils de légende de la Formule 1 a dépassé son père

    Nul doute qu’elle offrira à Mika la meilleure option pour poursuivre sa carrière dans le sport automobile. Et il n'est pas Andrei Arshavin, pour répondre à la question sur les attentes facilement et naturellement.
  • Manchester City vs. Burnley - Football Match Report

    Manchester City vs. Burnley - Football Match Report

    He was picking the ball out of the net within six minutes after James Tarkowski gave away possession and City swept upfield. Guardiola said Aguero had "just a reaction on the knee" and was hopeful the latest problem was not serious.
    India, Sri Lanka, Maldives agree to improve intel sharing

    India, Sri Lanka, Maldives agree to improve intel sharing

    This is the first time that NSA Ajit Doval participated in the trilateral dialogue as the group has not met since March 2014. Doval arrived in Colombo today for trilateral discussions among India, Sri Lanka and the Maldives.
    Les NTIC : avantages et inconvénients

    Les NTIC : avantages et inconvénients

    En effet, avoir mille et une tâches à accomplir à la fois, ça peut avoir des effets négatifs. En effet, les travailleurs effectuent les tâches beaucoup plus rapidement tout en conservant leur qualité de vie.
  • Amazon Prime Video acquires India rights for New Zealand cricket

    Amazon Prime Video acquires India rights for New Zealand cricket

    Notably, Prime members will get access to both men's and women's cricket held from 2021 to the 2025-2026 season. Amazon Prime Video starting to stream live cricket might break the duopoly that Star and Sony share in India.
    Why the Government of National Accord in Libya is illegitimate

    Why the Government of National Accord in Libya is illegitimate

    The most famous paramilitary organization that is part of the National Security Service of GNA is the «RADA» group. He is one of the main opponents of the Muslim Brotherhood in the region and one of the most famous fighters against terrorism.
    Choose Splento For Your Corporate Event Photography Solution in the US

    Choose Splento For Your Corporate Event Photography Solution in the US

    You may also have an upcoming corporate event anywhere in the US that you wish to make a permanent visual record of. As well as corporate event photography, Splento can also put you in touch with a headshot photography specialist.
  • Pfizer Begins Shipping COVID-19 Vaccine to US From Belgium

    Pfizer Begins Shipping COVID-19 Vaccine to US From Belgium

    Pfizer was the first of three - so far - pharmaceutical companies to publicize the results of its vaccine's phase 3 trial efficacy.
    Two teens shot and killed at California mall on Black Friday

    Two teens shot and killed at California mall on Black Friday

    He said customers and workers evacuated through the corridors and stairways in the back of the mall. About 40 homicides have been reported this year. "A gun is never the answer", he said.
    Milwaukee County vote recount gives Biden small boost

    Milwaukee County vote recount gives Biden small boost

    But more than 27,000 ballots that are part of the count have been segregated after objections by the Trump campaign. After the recount in Milwaukee county, Mr Biden had a net gain of 132 votes, out of almost 460,000 cast.


Populaire

Southampton boss Hasenhuttl addresses links with Manchester United hot seat
Marcus Rashford, Aaron Wan-Bissaka and Victor Lindelof remain doubtful . Donny van de Beek is expected to be fit for selection this weekend.

Une cartouche de Super Mario Bros 3 vendue 156 000 dollars !
Une somme record, qui fait de la cartouche le jeu vidéo le plus cher du monde. Au total, 20 participants ont contribué à la vente aux enchères.

India sets rules for commissions, surge pricing for Uber and Ola
Additionally, the state government may by way of a notification direct 2% over and above the fare towards the state exchequer. A similar charge will be levied if the rider cancels the trip, which will be split between the driver and the aggregator.

John Travolta thanks fans for their support after his wife's death
John Travolta is feeling grateful for his fans after the passing of his wife Kelly Preston in July. I found this photo of my mom and dad's wedding. "All my love, John".

Clashes break out in Paris over bill to limit filming of police
One video reportedly taken Saturday near the Bastille shows a vehicle that appears to have been lit on fire by protesters. Police in France fired tear gas shells at protesters who were demonstrating against police violence in Paris .

Netherlands Women defeated by the USA
Her second career worldwide goal came 2,722 days after her first on June 15, 2013, the longest span between goals in WNT history. The top-ranked Americans have won all nine matches they've played this year. "Obviously, this was a unusual year", he said.

'Saved by the Bell': Selena Gomez Kidney Joke Controversy
In 2015, Gomez went public with her lupus diagnosis, for which she had previously received chemotherapy. Soon after "Respect Selena Gomez " became one of the top trends on social media.

Florida State game cancelled after coronavirus issues within FSU program
"Our team underwent the mandated third-party testing yesterday and learned late last night that we had one positive test". Through games of November 21, the ACC has played 69 of its 78 scheduled games (88.5 percent).

Buccaneers' A.Q. Shipley May Have Career-Ending Injury
While Tom Brady is still figuring things out with his new team, he's still playing well aside from a few hiccups this season. He shouldered the responsibility for his own failures, without pulling anyone else's flaws into the discussion.

Georgia Trump Supporters Consider Election Boycott Over Fraud Claims
The judge further continued that charges require very specific allegations and proof, and the three-batch judge did not have it. Ellis added, "On to SCOTUS!" - an acronym for the Supreme Court of the United States.